DiSBAC₂(3)

Name: DiSBAC₂(3)

CAS Registry Number: 47623-98-3

CA Index Name: 4,6(1H,5H)-Pyrimidinedione, 5-[3-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-

Other Names: 4,6(1H,5H)-Pyrimidinedione, 5-[3-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidi-nyl)-2-propenylidene]-1,3-diethyldihydro-2-thioxo-; Bis(1,3-diethylthiobarbituric acid)trimethine oxonol; DiSBAC₂(3)

Merck Index Number: Not listed

Chemical / Dye Class: Oxonol

Molecular Formula: C₁₉H₂₄N₄O₄S₂

Molecular Weight: 436.55

Physical Form: Purple powder

Solubility: Soluble in ethanol, methanol, dimethyl sulfoxide

Melting Point: 545.0 ± 60.0 °C, pressure 760 Torr

pK_a: 3.72 ± 0.20, most acidic, temperature: 25 °C; —2.49 ± 0.20, most basic, temperature: 25 °C

Absorption (λ_max): 535 nm

Emission (λ_max): 560 nm

Synthesis: Synthetic methods

Staining Applications: Cells; clostridial toxin substrate; endothelial cells; lipid particles; myocardium; neurons; islets of Langerhans; epithelial cells

Biological Applications: Measuring membrane potential; ion channel screening assays; taste modulators screening assays; detecting cystic fibrosis transmembrane conductance regulator (CFTR); HCN channel modulators; BK channel openers

Industrial Applications: Photographic materials

Safety / Toxicity: No data available

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