DiOC₆(3)

Name: DiOC₆(3)

CAS Registry Number: 53213-82-4

CA Index Name: Benzoxazolium, 3-hexyl-2-[3-(3-hex-yl-2(3H)-benzoxazolylidene)-1-propen-1-yl]-, iodide (1:1)

Other Names: Benzoxazolium, 3-hexyl-2-[3-(3-hexyl-2(3H)-benzoxazolylidene)-1-propenyl]-, iodide; 3,3'-Di-hexyloxacarbocyanine iodide; D 273; DiOC₆(3); NK2280

Merck Index Number: Not listed

Chemical / Dye Class: Cyanine

Molecular Formula: C₂₉H₃₇IN₂O₂

Molecular Weight: 572.52

Physical Form: Red powder

Solubility: Soluble in ethanol, methanol, dimethyl sulfoxide

Melting Point: 222-224 °C

Absorption (λ_max): 484 nm

Emission (λ_max): 501 nm

Synthesis: Synthetic methods

Staining Applications: Mitochondria; endoplasmic reticulum; bacteria; fungi; nucleic acids; leukocytes; lymphocytes; microtubules; myelin; presynaptic nerve terminals; sperms; spores

Biological Applications: Detecting mitochondrial membrane potential, nucleic acid hybridization, prostate cancer, germination Bacillus anthracis spores; apoptosis assays; diagnostic assays; in photodynamic therapy; treating malaria, leishmaniasis, trypanosomiasis, trichomoniasis, neosporosis, coccidiosis

Industrial Applications: Photoresists; photography

Safety / Toxicity: Photodamage of microtubules and inactivation of organelle motility

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